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Non-cognate DNA damage prevents formation of active conformation of Y-family DNA polymerases DinB and pol kappa

Y-family DNA polymerases are specialized to copy damaged DNA and are associated with increased mutagenesis due to their low fidelity. It is believed that the mechanism of nucleotide selection by Y-family DNA polymerases involves conformational changes preceding nucleotidyl transfer but there is limi...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Nevin, Philip, Lu, Xueguang, Zhang, Ke, Engen, John R., Beuning, Penny J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504746/
https://ncbi.nlm.nih.gov/pubmed/25899385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13304
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