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Unprecedented mechanism employed by the Salmonella enterica EutT ATP:Co(I)rrinoid adenosyltransferase precludes adenosylation of incomplete Co(II)rrinoids

Three distinct families of ATP:corrinoid adenosyltransferases (ACATs) exist that are capable of converting vitamin B(12) derivatives to coenzyme B(12) by catalyzing the thermodynamically challenging reduction of Co(II)rrinoids to form “super-nucleophilic” Co(I) intermediates. While the structures an...

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Bibliografische gegevens
Gepubliceerd in:Angew Chem Int Ed Engl
Hoofdauteurs: Park, Kiyoung, Mera, Paola E., Moore, Theodore C., Escalante-Semerena, Jorge C., Brunold, Thomas C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504680/
https://ncbi.nlm.nih.gov/pubmed/25914129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201501930
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