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The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation
Of late, numerous prodrugs are widely used for therapy. The hemeprotein cytochrome P450 (CYP) catalyzes the activation of prodrugs to form active metabolites. Therefore, the activation of CYP function might allow the use of lower doses of prodrugs and decrease toxicity. We hypothesized that the addi...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4504516/ https://ncbi.nlm.nih.gov/pubmed/26181717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131793 |
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