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DARC 2.0: Improved Docking and Virtual Screening at Protein Interaction Sites

Over the past decade, protein-protein interactions have emerged as attractive but challenging targets for therapeutic intervention using small molecules. Due to the relatively flat surfaces that typify protein interaction sites, modern virtual screening tools developed for optimal performance agains...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gowthaman, Ragul, Lyskov, Sergey, Karanicolas, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504481/
https://ncbi.nlm.nih.gov/pubmed/26181386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131612
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