Assembly and peptide binding of major histocompatibility complex class II heterodimers in an in vitro translation system.

In vitro transcription/translation of HLA-DR1 cDNAs in the presence of microsomal membranes was used to study the association of major histocompatibility complex class II molecules with peptide and invariant chain (Ii) in the endoplasmic reticulum (ER). HLA-DR alpha and HLA-DR beta subunits assemble...

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Bibliographic Details
Main Authors: Hedley, M L, Urban, R G, Strominger, J L
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC45044/
https://ncbi.nlm.nih.gov/pubmed/7937979
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