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Folding and assembly of major histocompatibility complex class I heterodimers in the endoplasmic reticulum of intact cells precedes the binding of peptide

Major histocompatibility complex (MHC) class I molecules are heterotrimers consisting of a polymorphic H chain, beta 2-microglobulin (beta 2m) and peptide. Peptides are thought to associate early during biosynthesis but the order of assembly of class I molecules from their component subunits in inta...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191294/
https://ncbi.nlm.nih.gov/pubmed/8245776
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