EGCG reverses human neutrophil elastase-induced migration in A549 cells by directly binding to HNE and by regulating α1-AT

Lung carcinogenesis is a complex process that occurs in unregulated inflammatory environment. EGCG has been extensively investigated as a multi-targeting anti-tumor and anti-inflammatory compound. In this study, we demonstrated a novel mechanism by which EGCG reverses the neutrophil elastase-induced...

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Publicado no:Sci Rep
Main Authors: Xiaokaiti, Yilixiati, Wu, Haoming, Chen, Ya, Yang, Haopeng, Duan, Jianhui, Li, Xin, Pan, Yan, Tie, Lu, Zhang, Liangren, Li, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503950/
https://ncbi.nlm.nih.gov/pubmed/26177797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11494
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