Immune evasion activities of accessory proteins Vpu, Nef and Vif are conserved in acute and chronic HIV-1 infection

Heterosexual HIV-1 transmission has been identified as a genetic bottleneck and a single transmitted/founder (T/F) variant with reduced sensitivity to type I interferon initiates productive infection in most cases. We hypothesized that particularly active accessory protein(s) may confer T/F viruses...

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Библиографические подробности
Опубликовано в: :Virology
Главные авторы: Mlcochova, Petra, Apolonia, Luis, Kluge, Silvia F., Sridharan, Aishwarya, Kirchhoff, Frank, Malim, Michael H., Sauter, Daniel, Gupta, Ravindra K.
Формат: Artigo
Язык:Inglês
Опубликовано: Academic Press 2015
Предметы:
Brief Communication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503796/
https://ncbi.nlm.nih.gov/pubmed/25827531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.03.015
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