Small ncRNA Expression-Profiling of Blood from Hemophilia A Patients Identifies miR-1246 as a Potential Regulator of Factor 8 Gene

Hemophilia A (HA) is a bleeding disorder caused by deficiency of functional plasma clotting factor VIII (FVIII). Genetic mutations in the gene encoding FVIII (F8) have been extensively studied. Over a thousand different mutations have been reported in the F8 gene. These span a diverse range of mutat...

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Pubblicato in:PLoS One
Autori principali: Sarachana, Tewarit, Dahiya, Neetu, Simhadri, Vijaya L., Pandey, Gouri Shankar, Saini, Surbhi, Guelcher, Christine, Guerrera, Michael F., Kimchi-Sarfaty, Chava, Sauna, Zuben E., Atreya, Chintamani D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503767/
https://ncbi.nlm.nih.gov/pubmed/26176629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132433
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