Pentoxifylline Attenuates Proteinuria in Anti-Thy1 Glomerulonephritis via Downregulation of Nuclear Factor-κB and Smad2/3 Signaling

Anti-Thy1 glomerulonephritis is a rat nephritis model closely simulating human mesangial proliferative glomerulonephritis. It affects primarily the mesangium, yet displays substantial proteinuria during the course. This study investigated the molecular signals underlying proteinuria in this disease...

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Bibliografske podrobnosti
izdano v:Mol Med
Main Authors: Chen, Yung-Ming, Chiang, Wen-Chih, Yang, Yalin, Lai, Chun-Fu, Wu, Kwan-Dun, Lin, Shuei-Liong
Format: Artigo
Jezik:Inglês
Izdano: ScholarOne 2015
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503651/
https://ncbi.nlm.nih.gov/pubmed/25879629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00023
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