Sequential Myosin Phosphorylation Activates Tarantula Thick Filament via a Disorder-Order Transition

Phosphorylation of myosin regulatory light chain (RLC) N-terminal extension (NTE) activates myosin in thick filaments. RLC phosphorylation plays a primary regulatory role in smooth muscle and a secondary (modulatory) role in striated muscle, which is regulated by Ca(2+) via TnC/TM on the thin filame...

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Bibliografiska uppgifter
I publikationen:Mol Biosyst
Huvudupphovsmän: Espinoza-Fonseca, L. Michel, Alamo, Lorenzo, Pinto, Antonio, Thomas, David D., Padrón, Raúl
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503533/
https://ncbi.nlm.nih.gov/pubmed/26038232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5mb00162e
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