Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells

Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections, which comprise nearly 8% of the human genome(1). The most recently acquired human ERV is HERV-K (HML-2), which repeatedly infected the primate lineage both before and after the divergence of humans and chimpanzees(2,3). Un...

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Publicado no:Nature
Main Authors: Grow, Edward J., Flynn, Ryan A., Chavez, Shawn L., Bayless, Nicholas L., Wossidlo, Mark, Wesche, Daniel, Martin, Lance, Ware, Carol, Blish, Catherine A., Chang, Howard Y., Reijo Pera, Renee A., Wysocka, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503379/
https://ncbi.nlm.nih.gov/pubmed/25896322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14308
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