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Generation of Human Induced Pluripotent Stem Cells Using Epigenetic Regulators Reveals a Germ Cell-Like Identity in Partially Reprogrammed Colonies

Previous studies have shown that induced pluripotent stem cells (iPSCs) can be derived from fibroblasts by ectopic expression of four transcription factors, OCT4, SOX2, KLF4 and c-MYC using various methods. More recent studies have focused on identifying alternative approaches and factors that can b...

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Hlavní autoři: Goyal, Akshi, Chavez, Shawn L., Reijo Pera, Renee A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861446/
https://ncbi.nlm.nih.gov/pubmed/24349377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082838
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