Integrin α4β7 expression increases HIV susceptibility in activated cervical CD4+ T cells via an HIV attachment-independent mechanism

BACKGROUND: CD4+ T cells, the principal target in acute SIV and HIV infection, are crucial for the establishment and dissemination of HIV infection in mucosal tissues. Studies indicate that α4β7 CD4+ T cells are preferentially infected by HIV in vitro and during acute SIV infection. The integrin α4β...

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Bibliografiska uppgifter
I publikationen:J Acquir Immune Defic Syndr
Huvudupphovsmän: Ding, Jian, Tasker, Carley, Lespinasse, Pierre, Dai, Jihong, Fitzgerald-Bocarsly, Patricia, Lu, Wuyuan, Heller, Debra, Chang, Theresa L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503378/
https://ncbi.nlm.nih.gov/pubmed/26167616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000676
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