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Case-Only Exome Sequencing and Complex Disease Susceptibility Gene Discovery: Study Design Considerations
Whole exome sequencing (WES) provides an unprecedented opportunity to identify the potential etiologic role of rare functional variants in human complex diseases. Large-scale collaborations have generated germline WES data on patients with a number of diseases, especially cancer, but less often on h...
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| Publicado no: | J Med Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4503357/ https://ncbi.nlm.nih.gov/pubmed/25371537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2014-102697 |
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