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Design Considerations for Massively Parallel Sequencing Studies of Complex Human Disease
Massively Parallel Sequencing (MPS) allows sequencing of entire exomes and genomes to now be done at reasonable cost, and its utility for identifying genes responsible for rare Mendelian disorders has been demonstrated. However, for a complex disease, study designs need to accommodate substantial de...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151293/ https://ncbi.nlm.nih.gov/pubmed/21850262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023221 |
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