PQBP1 is a Proximal Sensor of the cGAS-dependent Innate Response to HIV-1

Dendritic cells (DCs) play a critical role in the immune response to viral infection through the facilitation of cell intrinsic antiviral activity and the activation of adaptive immunity. HIV-1 infection of DCs triggers an IRF3-dependent innate immune response, which requires the activity of cyclic...

詳細記述

保存先:
書誌詳細
出版年:Cell
主要な著者: Yoh, Sunnie M., Schneider, Monika, Seifried, Janna, Soonthornvacharin, Stephen, Akleh, Rana E., Olivieri, Kevin C., De Jesus, Paul D., Ruan, Chunhai, de Castro, Elisa, Ruiz, Pedro A., Germanaud, David, des Portes, Vincent, García-Sastre, Adolfo, König, Renate, Chanda, Sumit K.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503237/
https://ncbi.nlm.nih.gov/pubmed/26046437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.04.050
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