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PQBP1 is a Proximal Sensor of the cGAS-dependent Innate Response to HIV-1
Dendritic cells (DCs) play a critical role in the immune response to viral infection through the facilitation of cell intrinsic antiviral activity and the activation of adaptive immunity. HIV-1 infection of DCs triggers an IRF3-dependent innate immune response, which requires the activity of cyclic...
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| Опубликовано в: : | Cell |
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| Главные авторы: | , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4503237/ https://ncbi.nlm.nih.gov/pubmed/26046437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.04.050 |
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