Native-like in vivo folding of a circularly permuted jellyroll protein shown by crystal structure analysis.
A jellyroll beta-sandwich protein, the Bacillus beta-glucanase H(A16-M), is used to probe the role of N-terminal peptide regions in protein folding in vivo. A gene encoding H(A16-M) is rearranged to place residues 1-58 of the protein behind a signal peptide and residues 59-214. The rearranged gene i...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937966/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.22.10417 |
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