Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis

Aim: Organic anion-transporting polypeptides OATP1B1 and OATP1B3 are sinusoidal membrane transporters mediating liver uptake of a wide range of substrates including conjugated and unconjugated bilirubin, xenobiotics and drugs. Absence of OATP1Bs in the liver causes Rotor syndrome. Our aim was to cor...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Sticova, Eva, Lodererova, Alena, van de Steeg, Evita, Frankova, Sona, Kollar, Marek, Lanska, Vera, Kotalova, Radana, Dedic, Tomas, Schinkel, Alfred H, Jirsa, Milan
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503098/
https://ncbi.nlm.nih.gov/pubmed/26191226
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados