Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation**

Despite its central importance for understanding the molecular basis of Alzheimer's disease (AD), high-resolution structural information on amyloid β-peptide (Aβ) fibrils, which are intimately linked with AD, is scarce. We report an atomic-resolution fibril structure of the Aβ1-40 peptide with...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Schütz, Anne K, Vagt, Toni, Huber, Matthias, Ovchinnikova, Oxana Y, Cadalbert, Riccardo, Wall, Joseph, Güntert, Peter, Böckmann, Anja, Glockshuber, Rudi, Meier, Beat H
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2015
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502972/
https://ncbi.nlm.nih.gov/pubmed/25395337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201408598
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