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A thermostable, chromatographically purified Ebola nano-VLP vaccine

BACKGROUND: Filovirus virus-like particles (VLP) are strong immunogens with the potential for development into a safe, non-infectious vaccine. However, the large size and filamentous structure of this virus has heretofore made production of such a vaccine difficult. Herein, we present new assays and...

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Publicat a:J Transl Med
Autors principals: Carra, John H, Martins, Karen A O, Schokman, Rowena D, Robinson, Camenzind G, Steffens, Jesse T, Bavari, Sina
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502941/
https://ncbi.nlm.nih.gov/pubmed/26174690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0593-y
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