Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo.

Oct3/4, a hallmark of the earliest stages of embryogenesis, is expressed in undifferentiated embryonal carcinoma (EC) and embryonic stem (ES) cells. Oct3/4 gene expression is dependent on the promoter region, the proximal enhancer and the newly identified distal enhancer. We have analysed in vivo oc...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Minucci, S, Botquin, V, Yeom, Y I, Dey, A, Sylvester, I, Zand, D J, Ohbo, K, Ozato, K, Scholer, H R
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1996
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450286/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8631309/
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