Retinoic acid-mediated down-regulation of Oct3/4 coincides with the loss of promoter occupancy in vivo.
Oct3/4, a hallmark of the earliest stages of embryogenesis, is expressed in undifferentiated embryonal carcinoma (EC) and embryonic stem (ES) cells. Oct3/4 gene expression is dependent on the promoter region, the proximal enhancer and the newly identified distal enhancer. We have analysed in vivo oc...
Zapisane w:
| Wydane w: | EMBO J |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
1996
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450286/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8631309/ |
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