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Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein.

Human T-cell leukemia virus type I (HTLV-I) encodes a 40 kDa trans-acting protein, Tax, that regulates transcription of both the proviral and cellular genes, and can transform rat fibroblasts. To determine the functional importance of its trans-acting capacities in cell transformation, we have exami...

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Main Authors: Yamaoka, S, Inoue, H, Sakurai, M, Sugiyama, T, Hazama, M, Yamada, T, Hatanaka, M
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC450285/
https://ncbi.nlm.nih.gov/pubmed/8631308
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