Constitutive activation of NF-kappa B is essential for transformation of rat fibroblasts by the human T-cell leukemia virus type I Tax protein.

Human T-cell leukemia virus type I (HTLV-I) encodes a 40 kDa trans-acting protein, Tax, that regulates transcription of both the proviral and cellular genes, and can transform rat fibroblasts. To determine the functional importance of its trans-acting capacities in cell transformation, we have exami...

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Bibliographic Details
Published in:EMBO J
Main Authors: Yamaoka, S, Inoue, H, Sakurai, M, Sugiyama, T, Hazama, M, Yamada, T, Hatanaka, M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1996
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450285/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8631308/
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