Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity

Earlier studies reported allelic deletion of the essential autophagy regulator BECN1 in breast cancers implicating BECN1 loss, and likely defective autophagy, in tumorigenesis. Recent studies have questioned the tumor suppressive role of autophagy, as autophagy-related gene (Atg) defects generally s...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Cicchini, Michelle, Chakrabarti, Rumela, Kongara, Sameera, Price, Sandy, Nahar, Ritu, Lozy, Fred, Zhong, Hua, Vazquez, Alexei, Kang, Yibin, Karantza, Vassiliki
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Translational Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502817/
https://ncbi.nlm.nih.gov/pubmed/25483966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.34398
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