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WIPI2B links PtdIns3P to LC3 lipidation through binding ATG16L1

WIPI proteins, phosphatidylinositol 3-phosphate (PtdIns3P) binding proteins with β-propeller folds, are recruited to the omegasome following PtdIns3P production. The functions of the WIPI proteins in autophagosome formation are poorly understood. In a recent study, we reported that WIPI2B directly b...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Dooley, Hannah C, Wilson, Michael I, Tooze, Sharon A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502699/
https://ncbi.nlm.nih.gov/pubmed/25629784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2014.996029
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