IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis

Protective immunity against Mycobacterium tuberculosis (Mtb) requires IFNG. Besides, IFNG-mediated induction of autophagy suppresses survival of virulent Mtb in macrophage cell lines. We investigated the contribution of autophagy to the defense against Mtb antigen (Mtb-Ag) in cells from tuberculosis...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Rovetta, Ana I, Peña, Delfina, Hernández Del Pino, Rodrigo E, Recalde, Gabriela M, Pellegrini, Joaquín, Bigi, Fabiana, Musella, Rosa M, Palmero, Domingo J, Gutierrez, Marisa, Colombo, María I, García, Verónica E
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
Materias:
Brief Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502660/
https://ncbi.nlm.nih.gov/pubmed/25426782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.981791
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