IFNG-mediated immune responses enhance autophagy against Mycobacterium tuberculosis antigens in patients with active tuberculosis

Protective immunity against Mycobacterium tuberculosis (Mtb) requires IFNG. Besides, IFNG-mediated induction of autophagy suppresses survival of virulent Mtb in macrophage cell lines. We investigated the contribution of autophagy to the defense against Mtb antigen (Mtb-Ag) in cells from tuberculosis...

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Podrobná bibliografie
Vydáno v:Autophagy
Hlavní autoři: Rovetta, Ana I, Peña, Delfina, Hernández Del Pino, Rodrigo E, Recalde, Gabriela M, Pellegrini, Joaquín, Bigi, Fabiana, Musella, Rosa M, Palmero, Domingo J, Gutierrez, Marisa, Colombo, María I, García, Verónica E
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502660/
https://ncbi.nlm.nih.gov/pubmed/25426782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.981791
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