Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways

In cultured cells, not many mitochondria are degraded by mitophagy induced by physiological cellular stress. We observed mitophagy in HeLa cells using a method that relies on the pH-sensitive fluorescent protein Keima. With this approach, we found that mitophagy was barely induced by carbonyl cyanid...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Hirota, Yuko, Yamashita, Shun-ichi, Kurihara, Yusuke, Jin, Xiulian, Aihara, Masamune, Saigusa, Tetsu, Kang, Dongchon, Kanki, Tomotake
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Science Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502654/
https://ncbi.nlm.nih.gov/pubmed/25831013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1023047
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