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A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities

The vast majority of approved antidepressants and antipsychotics exhibit a complex pharmacology. The mechanistic understanding of how these psychotropic medications are related to adverse drug reactions (ADRs) is crucial for the development of novel drug candidates and patient adherence. This study...

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Vydáno v:Eur Neuropsychopharmacol
Hlavní autoři: Michl, Johanna, Scharinger, Christian, Zauner, Miriam, Kasper, Siegfried, Freissmuth, Michael, Sitte, Harald H., Ecker, Gerhard F., Pezawas, Lukas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502613/
https://ncbi.nlm.nih.gov/pubmed/25044049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euroneuro.2014.06.013
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