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Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor.

The Sup35p protein of yeast Saccharomyces cerevisiae is a homologue of the polypeptide chain release factor 3 (eRF3) of higher eukaryotes. It has been suggested that this protein may adopt a specific self-propagating conformation, similar to mammalian prions, giving rise to the [psi+] nonsense suppr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Paushkin, S V, Kushnirov, V V, Smirnov, V N, Ter-Avanesyan, M D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 1996
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8670813/
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