Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor.

The Sup35p protein of yeast Saccharomyces cerevisiae is a homologue of the polypeptide chain release factor 3 (eRF3) of higher eukaryotes. It has been suggested that this protein may adopt a specific self-propagating conformation, similar to mammalian prions, giving rise to the [psi+] nonsense suppr...

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Pubblicato in:	EMBO J
Autori principali:	Paushkin, S V, Kushnirov, V V, Smirnov, V N, Ter-Avanesyan, M D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450255/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8670813/
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