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The RNA 3' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA.

The cleavage stimulation factor (CstF), and the cleavage and polyadenylation specificity factor (CPSF) are necessary for 3'-terminal processing of polyadenylated mRNAs. To study the distribution of 3' cleavage factors in the nuclei of human T24 cells, monoclonal antibodies against the CstF 64 kDa su...

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Udgivet i:EMBO J
Principais autores: Schul, W, Groenhout, B, Koberna, K, Takagaki, Y, Jenny, A, Manders, E M, Raska, I, van Driel, R, de Jong, L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450226/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8654386/
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