Structural adaptations in the interaction of EcoRI endonuclease with methylated GAATTC sites.

We have studied the interaction of EcoRI endonuclease with oligonucleotides containing GAATTC sites bearing one or two adenine-N6-methyl groups, which would be in steric conflict with key protein side chains involved in recognition and/or catalysis in the canonical complex. Single-strand methylation...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Jen-Jacobson, L, Engler, L E, Lesser, D R, Kurpiewski, M R, Yee, C, McVerry, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450225/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8654385/
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