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The Endoplasmic Reticulum Stress Sensor Inositol-Requiring Enzyme 1α Augments Bacterial Killing through Sustained Oxidant Production

Bacterial infection can trigger cellular stress programs, such as the unfolded protein response (UPR), which occurs when misfolded proteins accumulate within the endoplasmic reticulum (ER). Here, we used the human pathogen methicillin-resistant Staphylococcus aureus (MRSA) as an infection model to p...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Abuaita, Basel H., Burkholder, Kristin M., Boles, Blaise R., O’Riordan, Mary X.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502229/
https://ncbi.nlm.nih.gov/pubmed/26173697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00705-15
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