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The Endoplasmic Reticulum Stress Sensor Inositol-Requiring Enzyme 1α Augments Bacterial Killing through Sustained Oxidant Production

Bacterial infection can trigger cellular stress programs, such as the unfolded protein response (UPR), which occurs when misfolded proteins accumulate within the endoplasmic reticulum (ER). Here, we used the human pathogen methicillin-resistant Staphylococcus aureus (MRSA) as an infection model to p...

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Publicado en:mBio
Autores principales: Abuaita, Basel H., Burkholder, Kristin M., Boles, Blaise R., O’Riordan, Mary X.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502229/
https://ncbi.nlm.nih.gov/pubmed/26173697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00705-15
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