The growth defect in Escherichia coli deficient in peptidyl-tRNA hydrolase is due to starvation for Lys-tRNA(Lys).

The existence of a conditional lethal temperature-sensitive mutant affecting peptidyl-tRNA hydrolase in Escherichia coli suggests that this enzyme is essential to cell survival. We report here the isolation of both chromosomal and multicopy suppressors of this mutant in pth, the gene encoding the hy...

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Publié dans:	EMBO J
Auteurs principaux:	Heurgué-Hamard, V, Mora, L, Guarneros, G, Buckingham, R H
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8654380/
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