Orthologs of a novel archaeal and of the bacterial peptidyl–tRNA hydrolase are nonessential in yeast

Peptidyl–tRNA hydrolase (encoded by pth) is an essential enzyme in all bacteria, where it releases tRNA from the premature translation termination product peptidyl–tRNA. Archaeal genomes lack a recognizable peptidyl–tRNA hydrolase (Pth) ortholog, although it is present in most eukaryotes. However, w...

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Detalhes bibliográficos
Main Authors: Rosas-Sandoval, Guillermina, Ambrogelly, Alexandre, Rinehart, Jesse, Wei, David, Cruz-Vera, L. Rogelio, Graham, David E., Stetter, Karl O., Guarneros, Gabriel, Söll, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139208/
https://ncbi.nlm.nih.gov/pubmed/12475929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222659199
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