Orthologs of a novel archaeal and of the bacterial peptidyl–tRNA hydrolase are nonessential in yeast

Peptidyl–tRNA hydrolase (encoded by pth) is an essential enzyme in all bacteria, where it releases tRNA from the premature translation termination product peptidyl–tRNA. Archaeal genomes lack a recognizable peptidyl–tRNA hydrolase (Pth) ortholog, although it is present in most eukaryotes. However, w...

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Bibliografiska uppgifter
Huvudupphovsmän: Rosas-Sandoval, Guillermina, Ambrogelly, Alexandre, Rinehart, Jesse, Wei, David, Cruz-Vera, L. Rogelio, Graham, David E., Stetter, Karl O., Guarneros, Gabriel, Söll, Dieter
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2002
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC139208/
https://ncbi.nlm.nih.gov/pubmed/12475929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222659199
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