Orthologs of a novel archaeal and of the bacterial peptidyl–tRNA hydrolase are nonessential in yeast

Peptidyl–tRNA hydrolase (encoded by pth) is an essential enzyme in all bacteria, where it releases tRNA from the premature translation termination product peptidyl–tRNA. Archaeal genomes lack a recognizable peptidyl–tRNA hydrolase (Pth) ortholog, although it is present in most eukaryotes. However, w...

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Bibliographische Detailangaben
Hauptverfasser: Rosas-Sandoval, Guillermina, Ambrogelly, Alexandre, Rinehart, Jesse, Wei, David, Cruz-Vera, L. Rogelio, Graham, David E., Stetter, Karl O., Guarneros, Gabriel, Söll, Dieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2002
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC139208/
https://ncbi.nlm.nih.gov/pubmed/12475929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222659199
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