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Orthologs of a novel archaeal and of the bacterial peptidyl–tRNA hydrolase are nonessential in yeast

Peptidyl–tRNA hydrolase (encoded by pth) is an essential enzyme in all bacteria, where it releases tRNA from the premature translation termination product peptidyl–tRNA. Archaeal genomes lack a recognizable peptidyl–tRNA hydrolase (Pth) ortholog, although it is present in most eukaryotes. However, w...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Rosas-Sandoval, Guillermina, Ambrogelly, Alexandre, Rinehart, Jesse, Wei, David, Cruz-Vera, L. Rogelio, Graham, David E., Stetter, Karl O., Guarneros, Gabriel, Söll, Dieter
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139208/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12475929/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222659199
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