Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro.

Core histones isolated from normal and butyrate-treated HeLa cells have been reconstituted into nucleosome cores in order to analyze the role of histone acetylation in enhancing transcription factor binding to recognition sites in nucleosomal DNA. Moderate stimulation of nucleosome binding was obser...

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Publié dans:	EMBO J
Auteurs principaux:	Vettese-Dadey, M, Grant, P A, Hebbes, T R, Crane- Robinson, C, Allis, C D, Workman, J L
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450183/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8665858/
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