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Vpu Exploits the Cross-Talk between BST2 and the ILT7 Receptor to Suppress Anti-HIV-1 Responses by Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) constitute a major source of type-I interferon (IFN-I) production during acute HIV infection. Their activation results primarily from TLR7-mediated sensing of HIV-infected cells. However, the interactions between HIV-infected T cells and pDCs that modulate this se...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Bego, Mariana G., Côté, Édouard, Aschman, Nick, Mercier, Johanne, Weissenhorn, Winfried, Cohen, Éric A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501562/
https://ncbi.nlm.nih.gov/pubmed/26172439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005024
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