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Elaidate, an 18-Carbon Trans-monoenoic Fatty Acid, but not Physiological Fatty Acids Increases Intracellular Zn(2+) in Human Macrophages

Artificial trans fatty acids promote atherosclerosis by blocking macrophage clearance of cell debris. Classical fatty-acid response mechanisms include TLR4-NF-κB activation, and Erk1/2 phosphorylation, but these may not indicate long-term mechanisms. Indeed, nuclear NF-κB was increased by 60 minute...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Zacherl, Janelle R., Tourkova, Irina, St Croix, Claudette M., Robinson, Lisa J., Peck Palmer, Octavia M., Mihalik, Stephanie J., Blair, Harry C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501488/
https://ncbi.nlm.nih.gov/pubmed/25358453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25002
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