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The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane

Many Rab GTPase effectors are membrane-tethering factors, that is, they physically link two apposed membranes before intracellular membrane fusion. In this study, we investigate the distinct binding factors needed on apposed membranes for Rab effector–dependent tethering. We show that the homotypic...

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Pubblicato in:Mol Biol Cell
Autori principali: Ho, Ruoya, Stroupe, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501362/
https://ncbi.nlm.nih.gov/pubmed/25995379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-04-0922
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