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The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane

Many Rab GTPase effectors are membrane-tethering factors, that is, they physically link two apposed membranes before intracellular membrane fusion. In this study, we investigate the distinct binding factors needed on apposed membranes for Rab effector–dependent tethering. We show that the homotypic...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Ho, Ruoya, Stroupe, Christopher
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501362/
https://ncbi.nlm.nih.gov/pubmed/25995379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-04-0922
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