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Icariin reduces α-synuclein over-expression by promoting α-synuclein degradation

The objectives of this study are to investigate the effects of icariin (a main component extracted from Epimedium) on over-expression of α-synuclein and to explore the underlying mechanisms. APPV717I transgenic (Tg) mice and A53T α-synuclein-transfected PC12 cells were used in this study. The conten...

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Bibliografische gegevens
Gepubliceerd in:Age (Dordr)
Hoofdauteurs: Zhang, Lan, Shen, Cong, Chu, Jin, Liu, Ying, Li, Yali, Zhang, Li, Li, Lin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501328/
https://ncbi.nlm.nih.gov/pubmed/26169945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-015-9811-z
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