Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells

BACKGROUND: Human lung mast cells (HLMCs) infiltrate the airway epithelium and airway smooth muscle (ASM) in asthmatic airways. The mechanism of HLMC adhesion to both cell types is only partly defined, and adhesion is not inhibited by function-blocking anti-Kit and anti-stem cell factor (SCF) antibo...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Gough, Kevin C., Maddison, Ben C., Shikotra, Aarti, Moiseeva, Elena P., Yang, Weidong, Jarvis, Shila, Bradding, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501212/
https://ncbi.nlm.nih.gov/pubmed/26173671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0245-z
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