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CADM1 isoforms differentially regulate human mast cell survival and homotypic adhesion

Cell adhesion molecule 1 (CADM1), expressed by human lung mast cells (HLMCs), mediates their adhesion to airway smooth muscle (ASM), and contributes to ASM-dependent HLMC proliferation and survival. CADM1 is expressed in alternatively spliced isoforms, but those present in HLMCs and their function a...

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Autori principali: Moiseeva, Elena P., Leyland, Mark L., Bradding, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: SP Birkhäuser Verlag Basel 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400039/
https://ncbi.nlm.nih.gov/pubmed/22438059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-0948-y
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