Fast and scalable inference of multi-sample cancer lineages

Somatic variants can be used as lineage markers for the phylogenetic reconstruction of cancer evolution. Since somatic phylogenetics is complicated by sample heterogeneity, novel specialized tree-building methods are required for cancer phylogeny reconstruction. We present LICHeE (Lineage Inference...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genome Biol
Main Authors: Popic, Victoria, Salari, Raheleh, Hajirasouliha, Iman, Kashef-Haghighi, Dorna, West, Robert B, Batzoglou, Serafim
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Method
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501097/
https://ncbi.nlm.nih.gov/pubmed/25944252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0647-8
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