Lineage commitment of transformed haematopoietic progenitors is determined by the level of PKC activity.
Our previous work showed that haematopoietic precursors transformed by the E26 avian leukemia virus undergo multilineage differentiation in response to the phorbol ester phorbol 12-myristate 13-acetate (PMA). Treatment of the cells with high concentrations of PMA (100 nM) favours myelomonocytic diff...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450108/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617236/ |
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